Neurons from skin mimic brain holes

Neurons from skin mimic brain holes

Huntington’s disease (HD) is a neurodegenerative disorder characterized by motor, behavioral and cognitive abnormalities that worsen until death. HD is caused by expansion of a CAG repeat tract of the huntingtin gene, encoding mutant Huntingtin (mHtt) protein with an expanded polyglutamine (polyQ) tract (> 39 Qs). The pathological hallmark of HD is the loss of medium spiny neurons (MSNs) in the...

Neuromechanics: From Neurons to Brain

Arguably, the brain is the most complex organ in the human body, and, at the same time, the least well understood. Today, more than ever before, the human brain has become a subject of narcissistic study and fascination. The fields of neuroscience, neurology, neurosurgery, and neuroradiology have seen tremendous progress over the past two decades; yet, the field of neuromechanics remains undera...

From Neurons to Brain: Adaptive Self-Wiring of Neurons

During embryonic morpho-genesis, a collection of individual neurons turns into a functioning network with unique capabilities. Only recently has this most staggering example of emergent process in the natural world, began to be studied. Here we propose a navigational strategy for neurites growth cones, based on sophisticated chemical signaling. We further propose that the embryonic environment ...

5G Technology: Why Should We Expect a shift from RF-Induced Brain Cancers to Skin Cancers?

From Spiking Neurons to Brain Waves

Two models of the neocortex are developed to study normal and pathological neuronal activity. One model contains a detailed description of a neocortical microcolumn represented by 656 neurons, including superficial and deep pyramidal cells, four types of inhibitory neurons and realistic synaptic contacts. Simulations show that neurons of a given type exhibit similar behavior in this detailed mo...